In order to improve the ability of integrated energy system to absorb new energy and reduce system operating cost,an optimal scheduling model is proposed by considering the integrated demand response and the integrated energy system of industrial park is taken as the research object. Firstly, the basic model of the park integrated energy system including CHP unit, gas boiler, electric boiler and other coupled equipment is established, and the flexible loads on the demand side of the system are divided into three types: transferable loads, interruptible loads, and replaceable loads. Among them, replaceable loads realizes the coordination and interaction between multiple types of energy. Secondly, the schedulable value of electric vehicles is discussed, combined with the timeofuse electricity price and load curves of the system, the charging and discharging of electric vehicles are orderly guided to participate in the optimal scheduling of integrated energy system. Finally, an example is included to verify the advantages of the proposed model in terms of operating cost, consumption of new energy and peak loads shaving .